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ATDC Ac-K116 Antibody (600-401-B16) in WB
Western blot using Rocklands affinity purified anti-ATDC (Ac-K116) antibody shows detection of a 66 kDa band corresponding to over-expressed, acetylated lysine (K116) ATDC (arrowhead) in transfected 293T cells. No staining is noted for cells transfected with empty vector only. No staining is noted for cells transfected with an ATDC K116R mutant (K to R transversion lacks site for acetylation). In each instance, samples were prepared with and without TSA (1.3µM, 6 hr) which inhibits deacetylation. Personal communication, Z. Yuan, H Lee Moff... View More
产品信息
600-401-B16
产品规格
种属反应
Bovine,
Chimpanzee,
Horse,
Human,
Rhesus monkey
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to an internal portion of human ATDC protein around lysine 116.
偶联物
形式
Liquid
浓度
0.67 mg/mL
纯化类型
Affinity chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
内含物
0.01% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This antibody reacts with over-expressed, acetylated lysine ATDC protein. A BLAST analysis was used to suggest cross-reactivity with ATDC from human, horse, cattle, chimpanzee and macaque based on a 100% homology with the immunizing sequence. Partial reactivity is expected against rat and mouse ATDC based on 92% homology with the immunizing sequence. Cross-reactivity with ATDC from other sources has not been determined.
靶标信息
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein; FLJ36085; tripartite motif protein TRIM29; tripartite motif-containing 29; Tripartite motif-containing protein 29
基因别名: ATDC; EGK_06995; TRIM29
UniProt ID: (Human) Q14134
Entrez Gene ID: (Human) 23650, (Rhesus monkey) 705796, (Bovine) 525062, (Horse) 100071461
