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产品信息
PA5-120901
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ATL1 (NP_056999.2).
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914473
产品详细信息
Positive test controls include: SH-SY5Y, LOVO, H460, 293T, U-87MG, U-251MG, Mouse brain. The target is usually found in the following locations: Cell projection, Endoplasmic reticulum membrane, Golgi apparatus membrane, Multi-pass membrane protein, axon.
Immunogen sequence: MAKNRRDRNS WGGFSEKTYE WSSEEEEPVK KAGPVQVLIV KDDHSFELDE TALNRILLSE AVRDKEVVAV SVAGAFRKGK SFLMDFMLRY MYNQESVDWV GDYNEPLTGF SWRGGSERET TGIQIWSEIF LINKPDGKKV AVLLMDTQGT FDSQSTLRDS ATVFALSTMI SSIQVYNLSQ NVQEDDLQHL QLFTEYGRLA MEETFLKPFQ SLIFLVRDWS FPYEFSYGAD GGAKFLEKRL KVSGNQHEEL QNVRKHIHSC FTNISCFLLP HPGLKVATNP
靶标信息
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATL1 alpha; ATL1 beta; ATL1 gamma; ATL1-delta; Atlastin-1; BCL-11B; Bcl11B; BCL11B/TRDC fusion; Brain-specific GTP-binding protein; Ctip 2; CTIP-2; CTIP2; GBP-3; GTP-binding protein 3; Guanine nucleotide-binding protein 3; guanylate-binding protein 3; hGBP3; hRit1; hRIT1 alpha; Rit 1; Rit1; Spastic paraplegia 3 protein A; Spastic paraplegia 3A homolog; ZNF856B
基因别名: 4930435M24Rik; AD-FSP; Adfsp; ATL1; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
UniProt ID: (Human) Q8WXF7, (Mouse) Q8BH66
Entrez Gene ID: (Human) 51062, (Mouse) 73991
