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AVPR1A Antibody (702609) in ICC/IF
For immunofluorescence analysis, HEK-293 cells were stably transfected with human AVPR1A. After 24hr of transfection the cells were fixed and permeabilized for detection of AVPR1A using Anti-AVPR1A Recombinant Rabbit Monoclonal Antibody (Product # 702609, 1 µg/mL, 1:500 dilution) and labeled with Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate. Panel a) shows representative cells that were stained for detection of membrane localization of the AVPR1A on the transfected cells. The images were captured a... View More
产品信息
702609
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
7H23L17
抗原
Peptide corresponding to human AVPR1A [aa398-aa418]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2734793
产品详细信息
This antibody is predicted to react with Monkey, Rabbit, Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Vasopressin receptor 1a (AVPR1A) is a receptor for arginine vasopressin. The activity of this receptor is mediated by G-proteins which activate a phosphatidyl-inositol-calcium second messenger system. AVPR1A has been involved in social behaviors, including affiliation and attachment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; AVPR V1a; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; V1a receptor; V1a vasopressin receptor; V1aR; Vascular/hepatic-type arginine vasopressin receptor; Vasopressin V1a receptor; Vasopressin V1aR
基因别名: AVPR; AVPR V1a; AVPR1; AVPR1A; V1a; V1aR
UniProt ID: (Human) P37288, (Rat) P30560
Entrez Gene ID: (Human) 552, (Rat) 25107
regulation of systemic arterial blood pressure by vasopressin
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
generation of precursor metabolites and energy
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
negative regulation of female receptivity
grooming behavior
blood circulation
positive regulation of cell proliferation
positive regulation of heart rate
positive regulation of glutamate secretion
myotube differentiation
calcium-mediated signaling
telencephalon development
positive regulation of cell growth
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
cellular response to hormone stimulus
social behavior
positive regulation of renal sodium excretion
cellular response to water deprivation
maternal behavior
sperm ejaculation
penile erection
positive regulation of vasoconstriction
response to corticosterone
negative regulation of transmission of nerve impulse
response to peptide
response to organic substance
response to inorganic substance
positive regulation of urine volume
positive regulation of blood pressure
positive regulation of glycogen catabolic process
regulation of corticotropin secretion
