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Suggested positive control: 293 whole cell lysate, HEK293 kidney cell lysates and MCC827 lung cell lysates.
Does not appear to work with A431 lysates.
Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bcl-2; BCS2; beclin 1, autophagy related, pseudogene 1; Beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1; Beclin-2; PFM 2; PFM2; PRDM 5; PRDM5; PRDM5 protein
基因别名: Beclin-2; BECN1L1; BECN1P1; BECN2; Gm104
UniProt ID: (Human) A8MW95, (Mouse) P0DM65
Entrez Gene ID: (Human) 441925, (Mouse) 226720