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C13orf15 Antibody (PA5-120573) in WB
Western blot analysis of C13orf15 in extracts of various cell lines. Samples were incubated with C13orf15 Polyclonal antibody (Product # PA5-120573) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-120573
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human RGCC (NP_054778.2).
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914145
产品详细信息
Positive test controls include: 293T, Mouse kidney, Mouse heart.
Immunogen sequence: ADFASPFHER HFHYEEHLER MKRRSSASVS DSSGFSDSES ADSLYRNSFS FSDEKLNSPT D
靶标信息
Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Regulator of cell cycle RGCC; Response gene to complement 32 protein; RGC-32
基因别名: 1190002H23Rik; bA157L14.2; C13orf15; RGC-32; RGC32; RGCC
UniProt ID: (Human) Q9H4X1, (Mouse) Q9DBX1, (Rat) Q9Z2P4
Entrez Gene ID: (Human) 28984, (Mouse) 66214, (Rat) 117183
negative regulation of exit from mitosis
negative regulation of endothelial cell proliferation
positive regulation of extracellular matrix constituent secretion
complement activation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of cell proliferation
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
negative regulation of angiogenesis
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
activation of protein kinase activity
positive regulation of collagen biosynthetic process
negative regulation of blood vessel endothelial cell migration
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine secretion
positive regulation of cytokine secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of stress fiber assembly
positive regulation of cell cycle arrest
cellular response to hypoxia
mitotic cell cycle arrest
fibroblast activation
negative regulation of fibroblast growth factor production
positive regulation of extracellular matrix assembly
negative regulation of mitotic cell cycle phase transition
negative regulation of cell-cell adhesion mediated by cadherin
positive regulation of endothelial cell apoptotic process
positive regulation of DNA biosynthetic process
G1/S transition of mitotic cell cycle
cell cycle
regulation of cell cycle
regulation of cyclin-dependent protein serine/threonine kinase activity
