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CACNA2D4 Antibody (PA5-88418) in WB
Western blot analysis of CACNA2D4 in extracts of various cell lines. Samples were incubated with CACNA2D4 Polyclonal antibody (Product # PA5-88418) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88418
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 992-1115 of human CACNA2D4 (NP_7589524)
偶联物
形式
Liquid
浓度
2.52 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804896
产品详细信息
Immunogen sequence: AKSVFHHSHK HKKQDPLQPC DTEYPVFVYQ PAIREANGIV ECGPCQKVFV VQQIPNSNLL LLVTDPTCDC SIFPPVLQEA TEVKYNASVK CDRMRSQKLR RRPDSCHAFH PEENAQDCGG ASDT; Positive Samples: HT-29, LO2; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
CACNA2D4 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium channel, voltage-dependent, alpha 2/delta subunit 4; Voltage-dependent calcium channel subunit alpha-2/delta-4; voltage-gated calcium channel alpha(2)delta-4 subunit; Voltage-gated calcium channel subunit alpha-2/delta-4
基因别名: CACNA2D4; RCD4
UniProt ID: (Human) Q7Z3S7
Entrez Gene ID: (Human) 93589
