Invitrogen

CALHM1 Polyclonal Antibody

CALHM1 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 3

CALHM1 Antibody (PA5-20895) in ICC/IF

Immunofluorescence of CALHM1 in Rat Liver cells with CALHM1 Polyclonal Antibody (Product # PA5-20895) at 20 µg/mL.

CALHM1 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

产品信息

PA5-20895

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

免疫组化 (IHC)

5 µg/mL

免疫细胞化学 (ICC/IF)

20 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A 17 amino acid peptide near the amino terminus of human CALHM1.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_11153561

产品详细信息

A suggested positive control is rat liver tissue lysate.

PA5-20895 can be used with blocking peptide PEP-1009.

靶标信息

Alzheimers disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.

仅用于科研。不用于诊断过程。未经明确授权不得转售。