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CCDC155 Antibody (PA5-54115) in IHC
Immunohistochemical staining of CCDC155 in human cerebral cortex, colon, lymph node and testis using CCDC155 Polyclonal Antibody (Product # PA5-54115) (A) shows similar protein distribution across tissues to an independent CCDC155 Polyclonal Antibody (B).
产品信息
PA5-54115
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639410
产品详细信息
Immunogen sequence: EENGKLLAER DGVKKRSQEL AMEKDTLKRQ LFECEHLICQ RDTILSERTR DVESLAQTLE EYRVTTQELR LEISRLEEQL SQTYEGPDEL PEGA
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 81%.
靶标信息
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly. Required for homolog pairing during meiotic prophase in spermatocytes and probably oocytes. Essential for male and female gametogenesis. Recruits cytoplasmic dynein to telomere attachment sites at the nuclear envelope in spermatocytes. In oocytes is involved in meiotic resumption and spindle formation. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coiled-coil domain-containing protein 155; KASH domain-containing protein 5; Protein KASH5
基因别名: CCDC155; KASH5
UniProt ID: (Human) Q8N6L0
Entrez Gene ID: (Human) 147872
