Invitrogen

CD105 Monoclonal Antibody (SN6), PE

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CD105 Antibody (MA1-80944) in Flow

PloS one 2019 - Fig 1 MSCs derived from horse peripheral blood expressed typical MSC markers and reduced lameness in horses with osteoarthritis. (A) Representative phenotype of MSC, gray line represents unstained cells; the red filled line represents cells stained with individual specific antibodies (CD105, CD146, CD90, CD73). (B) The AAEP lameness scale was used for grading lameness before and after six weeks. Autologous ... View More

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产品信息

MA1-80944

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

流式细胞分析 (Flow)

Neat

查看5篇已发表文章 5篇已发表文章

其他PubMed (MISC)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Horse, Human, Non-human primate

已发表种属

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

SN6

抗原

Cell membrane antigens from fresh leukemia cells.

查看免疫原

偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Lyophilized

浓度

Conc. Not Determined

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA, 5% sucrose

内含物

0.09% sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_927393

产品详细信息

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark.

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Mouse anti Human CD105 antibody, clone SN6 recognizes the human endoglin, also known as CD105. CD105 is a glycoprotein homodimer of approximately 95 kDa subunits expressed by endothelial cells, activated monocytes and some leukemia cells.

靶标信息

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.

International journal of molecular sciences

Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB

MA1-80944 was used in Flow Cytometry to investigate mitochondria damage induced by hyperglycemia-driven reactive species oxygen (ROS) accumulation and verified whether mesenchymal stem cells (MSCs) anti-oxidative, anti-apoptotic, autophagy modulation, and pro-mitochondria homeostasis therapeutic potential curtailed T2DM-DKD progression.

Thu Feb 04 00:00:00 UTC 2021

Peripheral blood-derived mesenchymal stem cells demonstrate immunomodulatory potential for therapeutic use in horses.

PloS one

Longhini ALF,Salazar TE,Vieira C,Trinh T,Duan Y,Pay LM,Li Calzi S,Losh M,Johnston NA,Xie H,Kim M,Hunt RJ,Yoder MC,Santoro D,McCarrel TM,Grant MB

Published figure using CD105 monoclonal antibody (Product # MA1-80944) in Flow Cytometry

Mon Nov 25 00:00:00 UTC 2019

Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models.

Blood

Dourado KMC,Baik J,Oliveira VKP,Beltrame M,Yamamoto A,Theuer CP,Figueiredo CAV,Verneris MR,Perlingeiro RCR

MA180944 was used in flow cytometry to explore the contribution of CD105 to leukemogenesis

Thu May 04 00:00:00 UTC 2017

Targeted introduction and effective expression of hFIX at the AAVS1 locus in mesenchymal stem cells.

Molecular medicine reports

Li SJ,Luo Y,Zhang LM,Yang W,Zhang GG

MA180944 was used in flow cytometry to develop mesenchymal stem cells derivatives to treat Hemophilia B

Wed Mar 01 00:00:00 UTC 2017

Differentiation of mesenchymal stem cells from human amniotic fluid to vascular endothelial cells.

Acta histochemica

Tancharoen W,Aungsuchawan S,Pothacharoen P,Markmee R,Narakornsak S,Kieodee J,Boonma N,Tasuya W

MA180944 was used in flow cytometry to describe and differentiate human amniotic fluid mesenchymal stem cells into endothelial-like cells

Wed Mar 01 00:00:00 UTC 2017

Mesenchymal stem cells differentiated into chondrocyte-Like cells.

Acta histochemica

Narakornsak S,Poovachiranon N,Peerapapong L,Pothacharoen P,Aungsuchawan S

MA1-80944 was used in flow cytometry and immunocytochemistry to study the differentiation of chondrocyte-like cells from mesenchymal stem cells

Sun May 01 00:00:00 UTC 2016

Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection.

PloS one

Avanzi S,Leoni V,Rotola A,Alviano F,Solimando L,Lanzoni G,Bonsi L,Di Luca D,Marchionni C,Alvisi G,Ripalti A

MA1-80944 was used in flow cytometry to assess the susceptibility of fetal membranes-derived mesenchymal stromal/stem cells to all members of the human Herpesviridae family.