Invitrogen

CD105 Monoclonal Antibody (SN6), PE

图: 1 / 6

CD105 Antibody (MHCD10504) in Flow

Antigen Specificity: According to the literature this antibody recognizes the CD105 antigen. Also known as endoglin, this antigen is expressed on endothelial cells, some bone marrow cells and activated macrophages.

Product Image Gallery

产品信息

MHCD10504

应用

建议稀释比

已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

流式细胞分析 (Flow)

Assay-Dependent

查看17篇已发表文章 17篇已发表文章

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human

已发表种属

Human, Sheep

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

SN6

抗原

Human CD105 (Endoglin)

偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Liquid

纯化类型

purified

保存液

PBS with sucrose, BSA

内含物

0.1% sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

AB_10392382

产品详细信息

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

靶标信息

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Analyte Specific Reagent

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury.

Stem cell research & therapy

Vaka R,Khan S,Ye B,Risha Y,Parent S,Courtman D,Stewart DJ,Davis DR

MHCD10504 was used in Flow Cytometry to assess the impact of inflammatory cytokines on the viability, and paracrine profile (extracellular vesicles) of bone marrow-derived mesenchymal stromal cells, heart-derived cells, and umbilical cord-derived mesenchymal stromal cells.

Sat Jan 15 00:00:00 UTC 2022

A bone-based 3D scaffold as an in-vitro model of microenvironment-DLBCL lymphoma cell interaction.

Frontiers in oncology

Ceccato J,Piazza M,Pizzi M,Manni S,Piazza F,Caputo I,Cinetto F,Pisoni L,Trojan D,Scarpa R,Zambello R,Tos APD,Trentin L,Semenzato G,Vianello F

MHCD10504 was used in Flow cytometry/Cell sorting to study the role of mesenchymal stromal cells (MSC) and the extracellular matrix (ECM) in the adaptation, growth, and drug resistance of DLBCL lymphoma cells in a developed 3D in-vitro model which was from human decellularized femoral bone fragments.

Sat Nov 05 00:00:00 UTC 2022

Effects of triptolide on bone marrow-derived mesenchymal stem cells from patients with multiple myeloma.

Experimental and therapeutic medicine

Wu H,Wu Y,Ren L,Zhai W,Jiang Y,Guo S,Tao D,Su C,Chen Z,Jiang H

MHCD10504 was used in Flow cytometry/Cell sorting to suggest that TPL inhibited BMMSC growth and improved the bone marrow hematopoietic microenvironment by decreasing IL-6, IL-1Β and SCF mRNA expression, subsequently inhibiting the proliferation of MM cells.

Wed May 01 00:00:00 UTC 2019

Derivation of Multipotent Mesenchymal Stromal Cells from Ovine Bone Marrow.

Current protocols in stem cell biology

Vivas D,Caminal M,Oliver-Vila I,Vives J

MHCD10504 was used in Flow Cytometry to describe methods which allow for the isolation, expansion, manipulation, and characterization of fibroblastic-like ovine bone marrow-derived multipotent mesenchymal stromal cells (BM-MSC) that, similar to human BM-MSC, adhere to standard plastic surfaces; express specific surface markers such as CD44, CD90, CD140a, CD105, and CD166; and display trilineage differentiation potential in vitro.

Wed Feb 28 00:00:00 UTC 2018

Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models.

Blood

Dourado KMC,Baik J,Oliveira VKP,Beltrame M,Yamamoto A,Theuer CP,Figueiredo CAV,Verneris MR,Perlingeiro RCR

MHCD10504 was used in flow cytometry to explore the contribution of CD105 to leukemogenesis

Thu May 04 00:00:00 UTC 2017

Cartilage resurfacing potential of PLGA scaffolds loaded with autologous cells from cartilage, fat, and bone marrow in an ovine model of osteochondral focal defect.

Cytotechnology

Caminal M,Peris D,Fonseca C,Barrachina J,Codina D,Rabanal RM,Moll X,Morist A,García F,Cairó JJ,Gòdia F,Pla A,Vives J

MHCD10504 was used in Flow Cytometry to evaluate their advantages as cartilage resurfacing agents.

Mon Aug 01 00:00:00 UTC 2016

Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering.

PloS one

Monsuur HN,Weijers EM,Niessen FB,Gefen A,Koolwijk P,Gibbs S,van den Broek LJ

MHCD10504 was used in Flow cytometry/Cell sorting to characterise endothelial cells from adipose tissue and compare them with endothelial cells from dermis.

Mon Sep 18 00:00:00 UTC 2017

PDE3A mutations cause autosomal dominant hypertension with brachydactyly.

Nature genetics

Maass PG,Aydin A,Luft FC,Schächterle C,Weise A,Stricker S,Lindschau C,Vaegler M,Qadri F,Toka HR,Schulz H,Krawitz PM,Parkhomchuk D,Hecht J,Hollfinger I,Wefeld-Neuenfeld Y,Bartels-Klein E,Mühl A,Kann M,Schuster H,Chitayat D,Bialer MG,Wienker TF,Ott J,Rittscher K,Liehr T,Jordan J,Plessis G,Tank J,Mai K,Naraghi R,Hodge R,Hopp M,Hattenbach LO,Busjahn A,Rauch A,Vandeput F,Gong M,Rüschendorf F,Hübner N,Haller H,Mundlos S,Bilginturan N,Movsesian MA,Klussmann E,Toka O,Bähring S

MHCD10504 was used in flow cytometry to discuss the contribution of missense mutations in PDE3A to hypertension.

Mon Jun 01 00:00:00 UTC 2015

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.

Stem cell reports

Cai J,Orlova VV,Cai X,Eekhoff EMW,Zhang K,Pei D,Pan G,Mummery CL,Ten Dijke P

Published figure using CD105 monoclonal antibody (Product # MHCD10504) in Flow Cytometry

Tue Dec 08 00:00:00 UTC 2015

Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity.

PloS one

Tasev D,van Wijhe MH,Weijers EM,van Hinsbergh VW,Koolwijk P

MHCD10504 was used in flow cytometry to investigate how xenogeneic-free conditions affect the therapeutic capacity of peripheral blood-derived endothelial-colony cells.

Wed Mar 02 00:00:00 UTC 2016

The isolation and culture of endothelial colony-forming cells from human and rat lungs.

Nature protocols

Alphonse RS,Vadivel A,Zhong S,McConaghy S,Ohls R,Yoder MC,Thébaud B

MHCD10504 was used in Immunohistochemistry to allow assessment of the functional state of these cells in experimental and human lung diseases, providing newer insights into their pathophysiological mechanisms.

Sun Nov 01 00:00:00 UTC 2015

Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.

Arteriosclerosis, thrombosis, and vascular biology

Orlova VV,Drabsch Y,Freund C,Petrus-Reurer S,van den Hil FE,Muenthaisong S,Dijke PT,Mummery CL

MHCD10504 was used in Flow cytometry/Cell sorting to demonstrate that vascular derivatives of hiPSC are fully functional and can be used to study defective endothelia-pericyte interactions in vitro.

Wed Jan 01 00:00:00 UTC 2014

Characterization and functionality of proliferative human Sertoli cells.

Cell transplantation

Chui K,Trivedi A,Cheng CY,Cherbavaz DB,Dazin PF,Huynh AL,Mitchell JB,Rabinovich GA,Noble-Haeusslein LJ,John CM

Published figure using CD105 monoclonal antibody (Product # MHCD10504) in Flow Cytometry

Thu Feb 09 00:00:00 UTC 2012

Promigratory activity of oxytocin on umbilical cord blood-derived mesenchymal stem cells.

Artificial organs

Kim YS,Kwon JS,Hong MH,Kim J,Song CH,Jeong MH,Cho JG,Park JC,Kang JC,Ahn Y

MHCD10504 was used in Flow cytometry/Cell sorting to evaluate the angiogenic potential and migration activity of oxytocin on mesenchymal stem cells.

Tue Jun 01 00:00:00 UTC 2010

Aging and replicative senescence have related effects on human stem and progenitor cells.

PloS one

Wagner W,Bork S,Horn P,Krunic D,Walenda T,Diehlmann A,Benes V,Blake J,Huber FX,Eckstein V,Boukamp P,Ho AD

MHCD10504 was used in Flow cytometry/Cell sorting to analyse the effect of aging on the gene expression profiles of human mesenchymal stromal cells and human haematopoietic progenitor cells.

Tue Jun 09 00:00:00 UTC 2009

Replicative senescence of mesenchymal stem cells: a continuous and organized process.

PloS one

Wagner W,Horn P,Castoldi M,Diehlmann A,Bork S,Saffrich R,Benes V,Blake J,Pfister S,Eckstein V,Ho AD

MHCD10504 was used in Flow cytometry/Cell sorting to study the impact of replicative senescence on human mesenchymal stem cells preparations.

Wed May 21 00:00:00 UTC 2008

Isolation and characterization of endothelial progenitor cells from human blood.

Current protocols in stem cell biology

Mead LE,Prater D,Yoder MC,Ingram DA

MHCD10504 was used in Flow Cytometry to describe detailed methodologies for isolation and characterization of endothelial colony-forming cells from both human peripheral and umbilical cord blood.

Tue Jul 01 00:00:00 UTC 2008

Mesenchymal stem cell features of Ewing tumors.

Cancer cell

Tirode F,Laud-Duval K,Prieur A,Delorme B,Charbord P,Delattre O

MHCD10504 was used in Flow Cytometry to characterise the mesenchymal stem cell features of Ewing tumours.

Tue May 01 00:00:00 UTC 2007

Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers.

Stem cells (Dayton, Ohio)

Mitchell JB,McIntosh K,Zvonic S,Garrett S,Floyd ZE,Kloster A,Di Halvorsen Y,Storms RW,Goh B,Kilroy G,Wu X,Gimble JM

MHCD10504 was used in Flow cytometry/Cell sorting to compare the immunophenotype of freshly isolated human adipose tissue-derived stromal vascular fraction cells relative to serial-passaged adipose-derived stem cells.