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产品信息
PA5-59603
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639539
产品详细信息
Immunogen sequence: LGPHNPTPPP SLDMFAEELA EEELETPTPT QRGEAESRGD GLVDVMWEYK WENTGDAELY GPFTSAQMQT WVSEGYFPDG VYCRKLDPPG GQFYNSKRID FDLY
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 89%.
靶标信息
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; U5 snRNP 52K protein; U5-52K
基因别名: CD2BP2; FWP010; KIAA1178; LIN1; PPP1R59; Snu40; U5-52K
UniProt ID: (Human) O95400
Entrez Gene ID: (Human) 10421
