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Immunogen sequence: KEHVLHCQFS AWYPFFRGVT IKSVILPLPQ NVKDYLLDDG TLVVSGRDDP PTHSQPDSDD EAEEIQWSDD ENTATLTAPE FPEFATKVQ
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.
The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid. The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase, and a homodimeric dihydrolipoamide dehydrogenase. E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cell division cycle 123 homolog; Cell division cycle protein 123 homolog; HT-1080; Protein D123; PZ32; Translation initiation factor eIF2 assembly protein
基因别名: C10orf7; CDC123; D123
UniProt ID: (Human) O75794
Entrez Gene ID: (Human) 8872