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CDC123 Antibody (MA5-36155) in WB
Western blot analysis of CDC123 using a CDC123 monoclonal antibody (Product #MA5-36155). Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody at a dilution of 1:500 was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: K562 cell lysate, Lane 2: A549 cell lysate
产品信息
MA5-36155
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE53-14
抗原
Recombinant protein within Human CDC123 aa 1-120
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2890382
靶标信息
The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid. The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase, and a homodimeric dihydrolipoamide dehydrogenase. E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell division cycle 123 homolog; Cell division cycle protein 123 homolog; HT-1080; Protein D123; PZ32; Translation initiation factor eIF2 assembly protein
基因别名: AA959893; C10orf7; CDC123; D123; G431001I09Rik
UniProt ID: (Human) O75794, (Mouse) Q8CII2
Entrez Gene ID: (Human) 8872, (Mouse) 98828
cell cycle
cell division
formation of cytoplasmic translation initiation complex
regulation of translation
cell cycle arrest
regulation of mitotic cell cycle
positive regulation of cell proliferation
positive regulation of translational initiation
eukaryotic translation initiation factor 2 complex assembly
