Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-31955
产品规格
种属反应
Fruit fly,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full length Drosophila CG1458 Recombinant protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2549428
产品详细信息
Recommended positive controls: Drosophila melanogaster (adult wild type), Cisd2 over express (actin promoter).
Predicted reactivity: Drosophila (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CDGSH iron-sulfur domain-containing protein 2; CDGSH iron-sulfur domain-containing protein 2 homolog; CG1458-PA; Cisd2-PA; Endoplasmic reticulum intermembrane small protein; Miner1; mitoNEET related 1; MitoNEET-related 1 protein; NAF-1; Nutrient-deprivation autophagy factor-1; RE49709p; RH38554p; zinc finger, CDGSH-type domain 2
基因别名: BcDNA:RE49709; CDGSH2; CG1458; CISD2; Dmel\CG1458; Dmel_CG1458; dWFS2; ERIS; Miner1; MitoNEET; NAF-1; WFS2; ZCD2
UniProt ID: (Human) Q8N5K1, (Fruit fly) Q9VAM6
Entrez Gene ID: (Human) 493856, (Fruit fly) 43459
