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Calpain 1 Antibody (MA1-13079) in IHC (P)
Immunohistochemistry was performed on human colon carcinoma tissue. Tissue was deparaffinized with xylene, followed by rehydration in sequential washes of 100% ethanol, 95% ethanol, 80% ethanol, and water. To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0) and heated for 20 min. Following antigen retrieval, tissues were blocked in a 3% BSA in wash buffer solution f... View More
产品信息
MA1-13079
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
P-6(2H7)
抗原
human erythrocyte Calpain-1 large subunit
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2-7.4
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2662441
产品详细信息
MA1-13079 detects calpain-1 large subunit (mu-type) in human and mouse samples by western blot, immunofluorescence, immunohistochemistry.
靶标信息
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium-activated neutral proteinase 1; calpain 1, (mu/I) large subunit; Calpain mu-type; calpain, large polypeptide L1; Calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP 1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Micromolar-calpain; mu-calpain; muCANP
基因别名: CANP; CANP1; CANPL1; Capa-1; Capa1; CAPN1; mu-calpin; muCANP; muCL; PIG30; SPG76
UniProt ID: (Human) P07384, (Mouse) O35350
Entrez Gene ID: (Human) 823, (Mouse) 12333
