Invitrogen

Caveolin 3 Polyclonal Antibody

查看其他10个Caveolin 3抗体

抗体检测数据 (6)

Caveolin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Caveolin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 6

Caveolin 3 Antibody (PA5-85274) in IHC (P)

Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Caveolin-3 (Product # PA5-85274) antibody at 1:500 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

Caveolin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Caveolin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Caveolin 3 Antibody in Western Blot (WB)

Caveolin 3 Antibody in Western Blot (WB)

Caveolin 3 Antibody in Western Blot (WB)

Caveolin 3 Antibody in Western Blot (WB)

Product Image Gallery

Caveolin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Caveolin-3 (Product # PA5-85274) antibody at 1:500 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

Caveolin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of Caveolin 3 in paraffin-embedded A549 xenograft using Caveolin 3 polyclonal antibody (Product # PA5-85274) at a dilution of 1:500.

Caveolin 3 Antibody in Western Blot (WB) — Western blot analysis of Caveolin 3 in mouse tissue extract using Caveolin 3 polyclonal antibody (Product # PA5-85274) using 50 µg of sample at a dilution of 1:1000. Prior to incubation with primary antibody, the sample was separated on 15% SDS-PAGE.

Caveolin 3 Antibody in Western Blot (WB) — Western blot analysis of Caveolin 3 in rat tissue extract using Caveolin 3 polyclonal antibody (Product # PA5-85274) using 50 µg of sample at a dilution of 1:1000. Prior to incubation with primary antibody, the sample was separated on 12% SDS-PAGE.

Caveolin 3 Antibody in Western Blot (WB) — Western Blot using Caveolin 3 Polyclonal Antibody (Product # PA5-85274). Mouse tissue extract (50 µg) was separated by 15% SDS-PAGE, and the membrane was blotted with Caveolin 3 Polyclonal Antibody (Product # PA5-85274) diluted at 1:1,000.

Caveolin 3 Antibody in Western Blot (WB) — Western Blot using Caveolin 3 Polyclonal Antibody (Product # PA5-85274). Rat tissue extract (50 µg) was separated by 12% SDS-PAGE, and the membrane was blotted with Caveolin 3 Polyclonal Antibody (Product # PA5-85274) diluted at 1:1,000.

产品信息

PA5-85274

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:20,000

-

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caveolin 3.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2792417

产品详细信息

Keep as concentrated solution.

Predicted reactivity: Dog (100%), Rhesus Monkey (100%), Bovine (100%).

Positive Control: Rat muscle, mouse muscle.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: CAV; Caveolin-3; M-caveolin; MGC126100; MGC126101; MGC126129

查看更多收起

基因别名: AI385751; Cav-3; CAV3; LGMD1C; LQT9; M-cav; VIP-21; VIP21

查看更多收起

UniProt ID: (Human) P56539, (Rat) P51638, (Mouse) P51637

查看更多收起

Entrez Gene ID: (Human) 859, (Rat) 29161, (Mouse) 12391

查看更多收起

calcium channel regulator activity protein binding protein C-terminus binding sodium channel regulator activity potassium channel inhibitor activity protein complex binding protein complex scaffold alpha-tubulin binding ion channel binding nitric-oxide synthase binding connexin binding enzyme binding scaffold/adaptor protein

plasma membrane repair regulation of heart rate negative regulation of protein kinase activity triglyceride metabolic process endocytosis muscle contraction plasma membrane organization actin filament organization positive regulation of cytosolic calcium ion concentration muscle organ development myoblast fusion regulation of heart contraction protein localization positive regulation of cell proliferation negative regulation of cardiac muscle hypertrophy positive regulation of myotube differentiation regulation of skeletal muscle contraction cell growth regulation of transforming growth factor beta receptor signaling pathway cell differentiation positive regulation of microtubule polymerization cytoplasmic microtubule organization membrane raft organization T-tubule organization detection of muscle stretch regulation of signal transduction by receptor internalization regulation of membrane potential glucose homeostasis cholesterol homeostasis negative regulation of MAP kinase activity negative regulation of MAPK cascade negative regulation of cell size muscle cell cellular homeostasis negative regulation of nitric-oxide synthase activity regulation of nerve growth factor receptor activity nucleus localization regulation of protein kinase B signaling negative regulation of calcium ion transport cardiac muscle cell development regulation of cardiac muscle contraction negative regulation of sarcomere organization regulation of ventricular cardiac muscle cell membrane repolarization heart trabecula formation regulation of ventricular cardiac muscle cell membrane depolarization regulation of branching involved in mammary gland duct morphogenesis negative regulation of cell growth involved in cardiac muscle cell development caveola assembly protein localization to plasma membrane ventricular cardiac muscle cell action potential establishment of protein localization to plasma membrane regulation of calcium ion import regulation of p38MAPK cascade regulation of membrane depolarization during cardiac muscle cell action potential negative regulation of membrane depolarization during cardiac muscle cell action potential negative regulation of potassium ion transmembrane transporter activity regulation of calcium ion transmembrane transporter activity negative regulation of potassium ion transmembrane transport negative regulation of protein localization to cell surface positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process regulation of sodium ion transmembrane transporter activity positive regulation of caveolin-mediated endocytosis myotube differentiation regulation of calcium ion transport