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Centrin 3 Antibody (PA5-35865) in ICC/IF
Centrin3 antibody detects Centrin3 protein at centrosome by immunofluorescent analysis. Sample: A549 cells were fixed in 100% MeOH for 5 min. Green: Centrin3 protein stained by Centrin3 antibody (Product # PA5-35865) diluted at 1:1,000. Red: alpha Tubulin Polyclonal Antibody [B-5-1-2] (Product # MA1-25054) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-35865
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 167 of Centrin3
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2553175
产品详细信息
Recommended positive controls: A549, H1299, HCT-116, Neuro2A, CD830, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (83%), Xenopus laevis (89%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC31 yeast homolog; centrin 3; centrin, EF-hand protein, 3 (CDC31 homolog, yeast); Centrin-3; EF-hand superfamily member
基因别名: CDC31; CEN3; CETN3; MmCEN3
UniProt ID: (Human) O15182, (Mouse) O35648
Entrez Gene ID: (Human) 1070, (Mouse) 12626, (Rat) 170895
