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产品信息
PA1-85314
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Collagen III from human placenta.
偶联物
形式
Lyophilized
浓度
0.1 mg/mL
纯化类型
purified
保存液
PBS/0.01M sodium borate with 1% dextran, 1% mannitol
内含物
no preservative
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_930088
产品详细信息
Reconstitute with 0.5 mL of distilled water. For long-term storage the addition of 0.09% sodium azide is recommended. Prior to reconstitution, store at 4ºC. After reconstitution, store undiluted at -20ºC, avoiding freeze/thaw cycles.
This antibody has been cross-absorbed with immobilized human collagen types I, IV and V and with human blood plasma proteins.
Rabbit anti Human collagen III antibody recognizes human collagen type III.
靶标信息
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
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生物信息学
蛋白别名: alpha1 (III) collagen; COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; Collagen3; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704
基因别名: COL3A1; EDS4A
UniProt ID: (Human) P02461
Entrez Gene ID: (Human) 1281
skeletal system development
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
heart development
aging
response to radiation
response to mechanical stimulus
peptide cross-linking
cerebral cortex development
platelet activation
extracellular matrix organization
collagen fibril organization
collagen catabolic process
response to cytokine
positive regulation of Rho protein signal transduction
wound healing
extracellular fibril organization
skin development
digestive tract development
regulation of immune response
negative regulation of immune response
aorta smooth muscle tissue morphogenesis
cellular response to amino acid stimulus
negative regulation of neuron migration
