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Recommended positive controls: A431, HeLa.
Predicted reactivity: Mouse (90%), Rat (93%), Dog (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 47 kDa cytokeratin; CK-13; cytokeratin 13; Cytokeratin-13; K-13; K13; keratin 13, type I; keratin complex 1, acidic, gene 13; Keratin, type I cytoskeletal 13; Keratin-13; MGC161462; MGC3781
基因别名: CK13; K13; Krt-1.13; Krt1-13; KRT13; WSN2
UniProt ID: (Human) P13646, (Mouse) P08730
Entrez Gene ID: (Human) 3860, (Mouse) 16663