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DUSP10 Antibody (PA5-106794) in ICC/IF
Immunocytochemistry analysis of DUSP10 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with DUSP10 polyclonal antibody (Product # PA5-106794) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-106794
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DUSP10(Accession Q9Y6W6), corresponding to amino acid residues H357-H407.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854462
产品详细信息
Antibody detects endogenous levels of total DUSP10.
靶标信息
Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. GPSN2 catalyzes the final step, reducing trans-2, 3-enoyl-CoA to saturated acyl-CoA. Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. TER catalyzes the final step, reducing trans-2, 3-enoyl-CoA to saturated acyl-CoA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: dual specificity phosphatase MKP-5; Dual specificity protein phosphatase 10; MAP kinase phosphatase 5; Mitogen-activated protein kinase phosphatase 5; serine/threonine specific protein phosphatase
基因别名: 2610306G15Rik; AI158871; DUSP10; MKP-5; MKP5
UniProt ID: (Human) Q9Y6W6, (Mouse) Q9ESS0
Entrez Gene ID: (Human) 11221, (Mouse) 63953, (Rat) 63995
inactivation of MAPK activity
regulation of adaptive immune response
protein dephosphorylation
response to stress
JNK cascade
dephosphorylation
response to lipopolysaccharide
peptidyl-tyrosine dephosphorylation
negative regulation of JUN kinase activity
negative regulation of protein kinase activity by regulation of protein phosphorylation
oligodendrocyte differentiation
negative regulation of oligodendrocyte differentiation
negative regulation of respiratory burst involved in inflammatory response
regulation of brown fat cell differentiation
negative regulation of stress-activated MAPK cascade
regulation of innate immune response
negative regulation of JNK cascade
response to organic substance
