Invitrogen

EHD1 Polyclonal Antibody

EHD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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EHD1 Antibody (PA5-98989) in IHC (P)

Immunohistochemical analysis of EHD1 in paraffin embedded human tonsil tissue using a EHD1 polyclonal antibody (Product # PA5-98989) at a dilution of 1:100.

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产品信息

PA5-98989

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

免疫组化（石蜡） (IHC (P))

1:20-1:200

酶联免疫吸附实验 (ELISA)

Assay-Dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human EH domain-containing protein 1 protein (401-498AA)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

4 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.03% ProClin 300

保存条件

-20°C or -80°C if preferred

运输条件

Wet ice

RRID

AB_2813602

靶标信息

EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。