Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-121071
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human ELF5 (NP_938195.1).
偶联物
形式
Liquid
浓度
0.75 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914643
产品详细信息
Positive test controls include: Rat lung, Rat kidney. The target is usually found in the following locations: Nucleus.
Immunogen sequence: EEYYPAFEHQ TACDSYWTSV HPEYWTKRHV WEWLQFCCDQ YKLDTNCISF CNFNISGLQL CSMTQEEFVE AAGLCGEYLY FILQNIRTQG YSFFNDAEES KATIKDYADS N
靶标信息
ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: E74-like factor 5; E74-like factor 5 (ets domain transcription factor); elf-5; Epithelium specific Ets-2; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2; ETS-related transcription factor Elf-5
基因别名: ELF5; ESE-2; ESE-5; ESE-5.; ESE2
UniProt ID: (Human) Q9UKW6, (Mouse) Q8VDK3
Entrez Gene ID: (Human) 2001, (Mouse) 13711, (Rat) 366142
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
ectodermal cell fate commitment
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell proliferation
cell differentiation
somatic stem cell population maintenance
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mammary gland epithelial cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
ectoderm development
