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产品信息
PA5-68805
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of mouse ELF5
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2688939
产品详细信息
This target displays homology in the following species: Cow: 86%; Dog: 86%; Guinea Pig: 85%; Horse: 92%; Human: 92%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
靶标信息
ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E74-like factor 5; elf-5; Epithelium specific Ets-2; ETS-related transcription factor Elf-5
基因别名: Elf5; ESE-2; ESE-5; ESE-5.
UniProt ID: (Mouse) Q8VDK3
Entrez Gene ID: (Mouse) 13711
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
ectodermal cell fate commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
ectoderm development
somatic stem cell population maintenance
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mammary gland epithelial cell differentiation
