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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELOF1 (Transcription elongation factor 1 homolog) is a 83 amino acid nuclear protein that is implicated in the maintenance of proper chromatin structure in regions that are being actively transcribed. The gene encoding ELOF1 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ELF1 homolog, elongation factor 1; elongation factor 1 homolog (ELF1, S. cerevisiae); Transcription elongation factor 1 homolog
基因别名: 1110011K10Rik; ELF1; ELOF1; RGD1309855
UniProt ID: (Human) P60002, (Mouse) P60003
Entrez Gene ID: (Human) 84337, (Mouse) 66126, (Rat) 691193