Invitrogen

ETV1 Polyclonal Antibody

ETV1 Antibody in Immunocytochemistry (ICC/IF)

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ETV1 Antibody (PA5-77975) in ICC/IF

ETV1 Polyclonal Antibody detects ER81 protein by immunofluorescent analysis. Sample: DIV9 rat hippocampal neuron and Glia cell cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ER81 stained by ETV1 Polyclonal Antibody (Product # PA5-77975) diluted at 1:250. Red: Tau, a Axon marker, stained by Tau antibody [GT287] diluted at 1:500.

ETV1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ETV1 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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产品信息

PA5-77975

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫组化（冰冻） (IHC (F))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human ER81. The exact sequence is proprietary.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.34 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2735767

产品详细信息

Positive Control: A431, Rat2

Predicted Reactivity: Xenopus laevis (86%), Chicken (92%), Chimpanzee (100%), Bovine (95%)

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DKFZp781L0674; ets related protein 81; ETS translocation variant 1; ets variant gene 1; Ets-related protein 81; MGC104699; MGC120533; MGC120534

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基因别名: ER81; Etsrp81; ETV1

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UniProt ID: (Human) P50549, (Mouse) P41164

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Entrez Gene ID: (Human) 2115, (Rat) 362733, (Mouse) 14009

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding sequence-specific DNA binding winged helix/forkhead transcription factor

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