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产品信息
PA5-52943
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human FBP2
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641523
产品详细信息
Immunogen sequence: RKAGLAHLYG IAGSVNVTGD EVKKLDVLSN SLVINMVQSS YSTCVLVSEE NKDAIITAKE KRGKYVVCFD PLDG
This product detects both FBP1 and FBP2, which are 80% homologous. The antigen sequence is a 100% match to FBP2 and the product has been validated against FBP1.
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
靶标信息
FBP1 and FBP2 are gluconeogenesis regulatory enzymes which catalyze the hydrolosis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; FBPase 1; FBPase 2; fructose-1; Fructose-1,6-bisphosphatase 1; fructose-1,6-bisphosphatase 2; Fructose-1,6-bisphosphatase isozyme 2; growth-inhibiting protein 17; hexosediphosphatase; Liver FBPase; Muscle FBPase; muscle fructose-bisphosphatase
基因别名: FBP; FBP1; FBP2
UniProt ID: (Human) P09467, (Human) O00757
Entrez Gene ID: (Human) 2203, (Human) 8789
fructose metabolic process
fructose catabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
dephosphorylation
negative regulation of cell growth
cellular response to drug
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
protein homotetramerization
cellular response to magnesium ion
