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Sequence of this protein is as follows: MAKVFSFILV TTALTMGREI SALEDCAQEQ MRLRAQVRLL ETRVKQQQVK IKQLLQENEV QFLDKGDENT VIDLGSKRQY ADCSEIFNDG YKLSGFYKIK PLQSPAEFSV YCDMSDGGGW TVIQRRSDGS ENFNRGWKDY ENGFGNFVQK HGEYWLGNKN LHFLTTQEDY TLKIDLADFE KNSRYAQYKN FKVGDEKNFY ELNIGEYSGT AGDSLAGNFH PEVQWWASHQ RMKFSTWDRD HDNYEGNCAE EDQSGWWFNR CHSANLNGVY YSGPYTAKTD NGIVWYTWHG WWYSLKSVVM KIRPNDFIPN VI
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: fibrinogen-like 1; Fibrinogen-like protein 1; Fibrinogen-related protein 1; Hepassocin; hepatocellular carcinoma-related sequence; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; HP-041; HPS; LFIRE-1; Liver fibrinogen-related protein 1; Liver fibrinogen-related protein-1; MFIRE-1; Mfrep-1; MGC12455; OTTHUMP00000122468
基因别名: FGL1; HFREP1; HP-041; LFIRE-1; LFIRE1; Mfire1
UniProt ID: (Human) Q08830, (Mouse) Q71KU9
Entrez Gene ID: (Human) 2267, (Mouse) 234199