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Sequence of this protein is as follows: EISALEDCAQ EQMRLRAQVR LLETRVKQQQ VKIKQLLQEN EVQFLDKGDE NTVIDLGSKR QYADCSEIFN DGYKLSGFYK IKPLQSPAEF SVYCDMSDGG GWTVIQRRSD GSENFNRGWK DYENGFGNFV QKHGEYWLGN KNLHFLTTQE DYTLKIDLAD FEKNSRYAQY KNFKVGDEKN FYELNIGEYS GTAGDSLAGN FHPEVQWWAS HQRMKFSTWD RDHDNYEGNC AEEDQSGWWF NRCHSANLNG VYYSGPYTAK TDNGIVWYTW HGWWYSLKSV VMKIRPNDFI PNVI
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: fibrinogen-like 1; Fibrinogen-like protein 1; Hepassocin; hepatocellular carcinoma-related sequence; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; HP-041; HPS; LFIRE-1; Liver fibrinogen-related protein 1; MGC12455; OTTHUMP00000122468
基因别名: FGL1; HFREP1; HP-041; LFIRE-1; LFIRE1
UniProt ID: (Human) Q08830
Entrez Gene ID: (Human) 2267