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产品信息
PA5-77097
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human FKBP6.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720824
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
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生物信息学
蛋白别名: 36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; FK506 binding protein 6, 36kDa; FK506-binding protein 6; FK506-binding protein 6 (36kD); FKBP-6; Immunophilin FKBP36; Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Inactive PPIase FKBP6; MGC87179; peptidyl-prolyl cis-trans isomerase FKBP6; PPIase FKBP6; rotamase
基因别名: 1700008G22Rik; 36kDa; As; AU017274; D5Ertd724e; FKBP-36; FKBP-6; FKBP36; FKBP6; PPiase
UniProt ID: (Human) O75344, (Mouse) Q91XW8, (Rat) D3ZQF4
Entrez Gene ID: (Human) 8468, (Mouse) 94244, (Rat) 288597
protein peptidyl-prolyl isomerization
protein folding
meiotic nuclear division
spermatogenesis
cell differentiation
gene silencing by RNA
piRNA metabolic process
DNA methylation involved in gamete generation
positive regulation of viral genome replication
chaperone-mediated protein folding
peptidyl-proline modification
meiotic cell cycle
