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产品信息
200-401-A58
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human FKBP8 protein.
偶联物
形式
Liquid
浓度
2.3 mg/mL
纯化类型
Protein A
保存液
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
内含物
0.01% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is specific for human FKBP8 protein. A BLAST analysis was used to suggest partial cross-reactivity with FKBP8 from mouse and rat sources based on ~93% homology with the immunizing sequence. Cross-reactivity with FKBP8 from other sources has not been determined.
靶标信息
FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, it does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 38 kDa FK506-binding protein; 38 kDa FKBP; FK506 binding protein 8, 38kDa; FK506-binding protein 38; FK506-binding protein 8; FK506-binding protein 8 (38kD); FKBP-38; FKBP-8; FKBPR38; hFKBP38; mFKBP38; Peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; Rotamase
基因别名: 38kDa; FKBP-38; FKBP-8; FKBP38; FKBP8; FKBPr38; Sam11
UniProt ID: (Human) Q14318, (Rat) Q3B7U9, (Mouse) O35465
Entrez Gene ID: (Human) 23770, (Rat) 290652, (Mouse) 14232
protein peptidyl-prolyl isomerization
cell fate specification
apoptotic process
smoothened signaling pathway
viral process
dorsal/ventral neural tube patterning
positive regulation of BMP signaling pathway
multicellular organism growth
intracellular signal transduction
camera-type eye development
negative regulation of apoptotic process
chaperone-mediated protein folding
dorsal/ventral pattern formation
regulation of gene expression
neural tube development
regulation of BMP signaling pathway
protein folding
