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产品信息
PA5-31334
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 65 and 296 of Human FVT1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548808
产品详细信息
Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (92%), Rat (92%), Xenopus laevis (81%), Chicken (84%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; follicular lymphoma variant translocation 1; Follicular variant translocation protein 1; FVT-1; KDS reductase; Short chain dehydrogenase/reductase family 35C member 1; short chain dehydrogenase/reductase family 35C, member 1
基因别名: DHSR; FVT1; KDSR; SDR35C1
UniProt ID: (Human) Q06136
Entrez Gene ID: (Human) 2531
