Invitrogen

Factor VIII Monoclonal Antibody (9035)

产品信息

MA1-43037

应用

建议稀释比

已发表文章

免疫印迹 (WB)

5-10 µg/mL

酶联免疫吸附实验 (ELISA)

5-10 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rat

分类

Monoclonal

类型

Antibody

克隆号

9035

抗原

Mouse Factor VIII.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

8.1 mg/mL

纯化类型

SDS-PAGE

保存液

50% water with 50% glycerol

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2101746

产品详细信息

MA1-43037 detects Factor VIII in mouse samples.

MA1-43037 has successfully been used in Western blot and ELISA applications.

MA1-43037 was derived from mouse factor VIII.

靶标信息

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

仅用于科研。不用于诊断过程。未经明确授权不得转售。