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产品信息
MA5-32323
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SN703
抗原
Recombinant protein within Human FosB aa 6-189
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2809605
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
c-FOS is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton, and is thought to have an important role in signal transduction, cell proliferation and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activator protein 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; fos b; FosB proto-oncogene, AP-1 trancription factor subunit; FosB proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 3; MGC42291; oncogene FOS-B; Protein FosB; Transcription factor AP-1 subunit FosB
基因别名: AP-1; FOSB; fra-2; G0S3; GOS3; GOSB
UniProt ID: (Human) P53539, (Rat) D3ZLB7, (Mouse) P13346
Entrez Gene ID: (Human) 2354, (Rat) 100360880, (Mouse) 14282
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor binding
RNA polymerase II regulatory region sequence-specific DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
protein heterodimerization activity
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
female pregnancy
response to mechanical stimulus
response to progesterone
cellular response to hormone stimulus
response to drug
response to morphine
positive regulation of transcription from RNA polymerase II promoter
response to corticosterone
response to cAMP
cellular response to calcium ion
regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
regulation of transcription, DNA-templated
