Invitrogen

GBP5 Polyclonal Antibody

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GBP5 Antibody (PA5-21809) in WB

Western Blot using GBP5 Polyclonal Antibody (Product # PA5-21809). Untreated (–) and treated (+) Raw264.7 whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with GBP5 Polyclonal Antibody (Product # PA5-21809) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

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产品信息

PA5-21809

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 1 and 213 of GBP5 (Uniprot ID#Q96PP8)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_11155238

产品详细信息

Recommended positive controls: 293T.

Predicted reactivity: Mouse (80%), Rat (80%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。