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Immunogen sequence: CLASRYGALV FMDECHATGF LGPTGRGTDE LLGVMDQVTI INSTLGKALG GASGGYTTGP GPLVSLLRQR ARPYLFSNSL PPAVVGCASK ALDLLMGSNT IVQSMAAKTQ RFRSKMEAAG FTISGA
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; 2-amino-3-ketobutyrate-CoA ligase; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase
基因别名: GCAT; KBL
UniProt ID: (Human) O75600
Entrez Gene ID: (Human) 23464