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产品信息
PA5-92390
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human GMNN (NP_0569791)
偶联物
形式
Liquid
浓度
0.36 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806471
产品详细信息
Immunogen sequence: MNPSMKQKQE EIKENIKNSS VPRRTLKMIQ PSASGSLVGR ENELSAGLSK RKHRNDHLTS TTSSPGVIVP ESSENKNLGG VTQESFDLMI KENPSSQYWK EVAEKRRKAL YEALKENEKL HKEIEQKDNE IARLKKENKE LAEVAEHVQY MAELIERLNG EPLDNFESLD NQEFDSEEET VEDSLVEDSE IGTCAEGTVS SSTDAKPCI; Positive Samples: SW480, 22Rv1, HL-60, MCF7, K-562; Cellular Location: Cytoplasm, Nucleus
靶标信息
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Geminin; Geminin GMNN; OTTHUMP00000039393; RP3 369A17.3
基因别名: AW546347; Gem; GMNN; MGORS6
UniProt ID: (Human) O75496, (Mouse) O88513
Entrez Gene ID: (Human) 51053, (Rat) 291137, (Mouse) 57441
