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GPR116 Antibody (PA5-75810) in WB
Western blot analysis of GPR116 in Lane 1: 3T3-L1 whole cell lysate (40 µg), Lane 2: PC12 whole cell lysate (40 µg), Lane 3: HEK293T whole cell lysate (40 µg), Lane 4: A549 whole cell lysate (40 µg). Samples were incubated with GPR116 polyclonal antibody (Product # PA5-75810) at a dilution of 1:500.
产品信息
PA5-75810
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human GPR116
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719538
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Adhesion G protein-coupled receptor F5; DKFZp564O1923; FLJ90640; G protein-coupled hepta-helical receptor Ig-Hepta; G protein-coupled receptor 116; G-protein coupled hepta-helical receptor Ig-hepta; G-protein coupled receptor 116; Ig-Hepta homolog; probable G-protein coupled receptor 116
基因别名: 8430401C09Rik; 9330185D23; ADGRF5; AI528491; GPR116; Gprhep; Ig-Hepta; KIAA0758; KPG_001; mKIAA0758
UniProt ID: (Human) Q8IZF2, (Mouse) G5E8Q8, (Rat) Q9WVT0
Entrez Gene ID: (Human) 221395, (Mouse) 224792, (Rat) 245977
energy reserve metabolic process
G-protein coupled receptor signaling pathway
regulation of lipid metabolic process
glucose homeostasis
surfactant homeostasis
fat cell differentiation
cell surface receptor signaling pathway
negative regulation of macrophage activation
positive regulation of phospholipid biosynthetic process
