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GluR2/GluR3 Antibody (MA5-49790) in ICC/IF
Immunocytochemistry analysis of MCF-7 cells with GluR2/GluR3 monoclonal antibody (Product # MA5-49790) at 1:56, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H... View More
产品信息
MA5-49790
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4C3
抗原
A synthesized peptide derived from human GRIA2/GRIA3
偶联物
形式
Liquid
浓度
1.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3093946
靶标信息
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AMPA-selective glutamate receptor 2; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluR-2; GluR-3; GluR-B; GluR-C; GluR-K2; GluR-K3; glutamate receptor; Glutamate receptor 2; Glutamate receptor 3; glutamate receptor B flip isoform; glutamate receptor C; Glutamate receptor ionotropic, AMPA 2; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 3; GPRC1C; GRM3; MGR3
基因别名: GluA2; GluA3; GLUR-C; GluR-K2; GLUR-K3; GLUR2; GLUR3; GLURB; GLURC; GRIA2; GRIA3; HBGR2; MRX94
UniProt ID: (Human) P42262, (Human) P42263
Entrez Gene ID: (Human) 2891, (Human) 2892
