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Peptide sequence: INKLQELQVN LVRSHSSGVG KPLSPERCRM LLALRINVLA KGYSGISLET
Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Histidase; Histidine ammonia-lyase
基因别名: HAL; HIS; HSTD
UniProt ID: (Human) P42357
Entrez Gene ID: (Human) 3034