HES1 Recombinant Rabbit Monoclonal Antibody (ARC0513)

RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding JUN kinase binding protein complex binding protein homodimerization activity histone deacetylase binding sequence-specific DNA binding protein dimerization activity chaperone binding E-box binding N-box binding basic helix-loop-helix transcription factor

negative regulation of transcription from RNA polymerase II promoter in utero embryonic development liver development embryonic heart tube morphogenesis outflow tract morphogenesis regulation of secondary heart field cardioblast proliferation ventricular septum development transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter protein complex assembly cell adhesion Notch signaling pathway smoothened signaling pathway STAT protein import into nucleus pattern specification process positive regulation of cell proliferation positive regulation of gene expression negative regulation of gene expression negative regulation of neuron projection development cell migration telencephalon development midbrain-hindbrain boundary morphogenesis oculomotor nerve development trochlear nerve development hindbrain morphogenesis forebrain radial glial cell differentiation neural tube development pituitary gland development adenohypophysis development lung development positive regulation of BMP signaling pathway midbrain development pancreas development somatic stem cell population maintenance hair cell differentiation aorta morphogenesis ascending aorta morphogenesis positive regulation of T cell proliferation auditory receptor cell differentiation positive regulation of tyrosine phosphorylation of Stat3 protein auditory receptor cell fate determination positive regulation of DNA binding regulation of protein heterodimerization activity cell fate commitment negative regulation of cell differentiation regulation of fat cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of neuron differentiation positive regulation of glial cell differentiation positive regulation of Notch signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of mitotic cell cycle, embryonic lateral inhibition positive regulation of JAK-STAT cascade cell maturation regulation of timing of cell differentiation thymus development cell morphogenesis involved in neuron differentiation positive regulation of astrocyte differentiation negative regulation of oligodendrocyte differentiation artery morphogenesis regulation of neurogenesis negative regulation of neurogenesis regulation of timing of neuron differentiation negative regulation of glial cell proliferation ventricular septum morphogenesis labyrinthine layer blood vessel development common bile duct development negative regulation of stomach neuroendocrine cell differentiation cardiac neural crest cell development involved in outflow tract morphogenesis pharyngeal arch artery morphogenesis cochlea development negative regulation of calcium ion import vascular smooth muscle cell development neuronal stem cell population maintenance negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding positive regulation of protein targeting to mitochondrion cellular response to nerve growth factor stimulus negative regulation of pancreatic A cell differentiation negative regulation of stem cell differentiation negative regulation of pro-B cell differentiation negative regulation of forebrain neuron differentiation negative regulation of inner ear receptor cell differentiation response to organic cyclic compound neuron differentiation response to alkaloid ureteric bud morphogenesis cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to fatty acid glomerulus vasculature development comma-shaped body morphogenesis S-shaped body morphogenesis renal interstitial fibroblast development metanephric nephron tubule morphogenesis response to thyroid hormone