Search Thermo Fisher Scientific
Immunogen sequence: ASFFSFRVSQ DAAPGSPLDK LVSSTSDLPK RLASRKCVSP EEFTEIMNQR EQFYHKVNFS PPG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); HMG-CoA synthase; Hydroxymethylglutaryl-CoA synthase, mitochondrial; testicular tissue protein Li 88
基因别名: HMGCS2
UniProt ID: (Human) P54868
Entrez Gene ID: (Human) 3158