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The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IGF; Insulin like growth factor; PEG8/IGF2AS protein
基因别名: IGF2-AS1; IGF2AS; PEG8
Entrez Gene ID: (Human) 51214