Invitrogen

INSRR Polyclonal Antibody

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INSRR Antibody (PA5-120068) in WB

Western blot analysis of INSRR in extracts of various cell lines. Samples were incubated with INSRR Polyclonal antibody (Product # PA5-120068) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

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产品信息

PA5-120068

应用

建议稀释比

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免疫印迹 (WB)

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 747-921 of human INSRR (NP_055030.1).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.39 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2913640

产品详细信息

Positive test controls include: Mouse brain, Mouse liver, Mouse kidney, Rat kidney. The target is usually found in the following locations: Membrane, Single-pass type I membrane protein.

Immunogen sequence: AAGPLRLGGN SSDFEIQEDK VPRERAVLSG LRHFTEYRID IHACNHAAHT VGCSAATFVF ARTMPHREAD GIPGKVAWEA SSKNSVLLRW LEPPDPNGLI LKYEIKYRRL GEEATVLCVS RLRYAKFGGV HLALLPPGNY SARVRATSLA GNGSWTDSVA FYILGPEEED AGGLH

靶标信息

INSRR, insulin receptor-related receptor, is a member of the insulin receptor (IR) family. INSRR does not bind insulin-like molecules, but is similar to INSR in tyrosine kinase activity. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

仅用于科研。不用于诊断过程。未经明确授权不得转售。