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产品信息
PA5-107154
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal region of Human KLF9
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.4, with 2% sucrose
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2817870
产品详细信息
Sequence homology: Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
靶标信息
KLF-9 is a transcription factor belonging to the Sp 1 C2H2 type zinc finger family. It binds to GC box elements located in the promoter. This binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. KLF-9 serves as a key transcriptional regulator for uterine endometrial cell proliferation, adhesion, and differentiation both during pregnancy and tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: basic transcription element binding protein 1; Basic transcription element-binding protein 1; BTE-binding protein 1; GC-box-binding protein 1; Krueppel-like factor 9; Kruppel-like factor 9; Transcription factor BTEB1
基因别名: BTEB; BTEB1; KLF9
UniProt ID: (Human) Q13886, (Rat) Q01713
Entrez Gene ID: (Human) 687, (Rat) 117560
DNA binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
nucleic acid binding
C2H2 zinc finger transcription factor
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
circadian rhythm
negative regulation of keratinocyte proliferation
cellular response to cortisol stimulus
cellular response to thyroid hormone stimulus
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
embryo implantation
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
progesterone receptor signaling pathway
cellular response to peptide
