Invitrogen

LPL Polyclonal Antibody

抗体检测数据 (3)

LPL Antibody in Immunocytochemistry (ICC/IF)

LPL Antibody in Immunocytochemistry (ICC/IF)

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LPL Antibody (PA5-85126) in ICC/IF

Immunocytochemistry analysis of LPL in 4% paraformaldehyde-fixed human embryonic stem cells (D3) using LPL polyclonal antibody (Product # PA5-85126) at a dilution of 1:200.

LPL Antibody in Immunocytochemistry (ICC/IF)

LPL Antibody in Western Blot (WB)

LPL Antibody in Western Blot (WB)

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LPL Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry analysis of LPL in 4% paraformaldehyde-fixed human embryonic stem cells (D3) using LPL polyclonal antibody (Product # PA5-85126) at a dilution of 1:200.

LPL Antibody in Western Blot (WB) — Western blot analysis of LPL in A) NIH-3T3 cells using LPL polyclonal antibody (Product # PA5-85126) using 30 µg of sample at a dilution of 1:1000. Prior to incubation with primary antibody, the sample was separated on 10% SDS PAGE.

LPL Antibody in Western Blot (WB) — Western blot analysis of LPL in A) Molt-4 cells using LPL polyclonal antibody (Product # PA5-85126) using 30 µg of sample at a dilution of 1:1000. Prior to incubation with primary antibody, the sample was separated on 10% SDS PAGE.

产品信息

PA5-85126

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

- -

免疫细胞化学 (ICC/IF)

1:100-1:1,000

-

产品规格

种属反应

Chicken, Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human LPL.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.11 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2792273

产品详细信息

Keep as concentrated solution.

Predicted reactivity: Mouse (90%), Rat (90%), Cat (94%), Pig (93%), Rabbit (92%), Sheep (91%), Bovine (91%), Guinea pig (86%).

Positive Control: Molt-4, NIH-3T3.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: adipose lipoprotein lipase; alpha lipase; Lipoprotein lipase; LPL; O 1-4-5; Phospholipase A1; triacylglycerol lipase

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基因别名: HDLCQ11; LIPD; LPL

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UniProt ID: (Chicken) P11602, (Human) P06858, (Mouse) P11152

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Entrez Gene ID: (Chicken) 396219, (Human) 4023, (Mouse) 16956

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lipoprotein lipase activity phospholipase activity triglyceride lipase activity receptor binding calcium ion binding heparin binding phosphatidylcholine 1-acylhydrolase activity lipase activity apolipoprotein binding protein homodimerization activity heparan sulfate proteoglycan binding phosphatidylserine 1-acylhydrolase activity 1-acyl-2-lysophosphatidylserine acylhydrolase activity lipoprotein particle binding protein binding triglyceride binding hydrolase activity carboxylic ester hydrolase activity lipase

参与通路

fatty acid metabolic process fatty acid biosynthetic process response to bacterium positive regulation of macrophage derived foam cell differentiation positive regulation of cholesterol storage positive regulation of sequestering of triglyceride lipid catabolic process triglyceride catabolic process cellular response to nutrient chylomicron remodeling very-low-density lipoprotein particle remodeling cholesterol homeostasis positive regulation of fat cell differentiation positive regulation of inflammatory response low-density lipoprotein particle mediated signaling triglyceride homeostasis cellular response to fatty acid positive regulation of chemokine secretion positive regulation of tumor necrosis factor secretion retinoid metabolic process triglyceride metabolic process phospholipid metabolic process response to cold response to glucose triglyceride biosynthetic process lipoprotein metabolic process response to drug lipid metabolic process