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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp586O1624; integral membrane glycoprotein; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine-rich repeats and immunoglobulin-like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; ortholog of mouse integral membrane glycoprotein LIG-1
基因别名: D6Bwg0781e; Img; LIG-1; LIG1; LRIG1
UniProt ID: (Human) Q96JA1, (Mouse) P70193
Entrez Gene ID: (Human) 26018, (Mouse) 16206