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Recommended positive controls: HeLa, HeLa nucleus, mouse heart.
Predicted reactivity: Mouse (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ53540; Mam-1; MAML1; mastermind homolog; mastermind-like 1; Mastermind-like protein 1; mastermind-like transcriptional coactivator 1
基因别名: AI644666; AW743257; D930008C07Rik; KIAA0200; Mam-1; Mam1; MAML1; mKIAA0200
UniProt ID: (Human) Q92585, (Mouse) Q6T264
Entrez Gene ID: (Human) 9794, (Mouse) 103806