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产品信息
PA5-43669
产品规格
种属反应
Human
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human MAS1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2609752
产品详细信息
Peptide sequence: VIIFIAILSF LVFTPLMLVS STILVVKIRK NTWASHSSKL YIVIMVTIII
Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Rat: 100%
靶标信息
The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a 7-transmembrane segment following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Mas-related G protein-coupled receptor A; MAS1 oncogene; Mas1 proto-oncogene; MGC119966; Proto-oncogene Mas
基因别名: MAS; MAS1; MGRA
UniProt ID: (Human) P04201
Entrez Gene ID: (Human) 4142
negative regulation of protein phosphorylation
G-protein coupled receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
spermatogenesis
cell proliferation
positive regulation of cell proliferation
male gonad development
anatomical structure morphogenesis
response to activity
hippocampus development
response to gonadotropin
angiotensin-activated signaling pathway
response to drug
positive regulation of DNA replication
regulation of inflammatory response
positive regulation of inositol phosphate biosynthetic process
protein kinase C signaling
