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MASP1 Antibody (PA5-119268) in IHC (P)
Immunohistochemistry analysis of MASP1 in paraffin-embedded Human Colorectal cancer tissue. Samples were incubated with polyclonal antibody (Product # PA5-119268) at a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
产品信息
PA5-119268
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Mannose Associated Serine Protease 1. The antigen corresponds to amino acid range 20-447 of the target protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903766
靶标信息
MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C4/C2 activating component of Ra-reactive factor; Complement factor MASP-3; Complement-activating component of Ra-reactive factor; mannan-binding; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); Mannan-binding lectin serine protease 1; Mannose-binding lectin-associated serine protease 1; Mannose-binding protein-associated serine protease; MASP-1; Ra-reactive factor serine protease p100; RaRF; Serine protease 5
基因别名: 3MC1; CRARF; CRARF1; MAP1; MAp44; MASP; MASP1; MASP3; PRSS5; RaRF
UniProt ID: (Human) P48740
Entrez Gene ID: (Human) 5648
