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MCFD2 Antibody (PA5-48016) in IHC (F)
Immunohistochemical analysis of MCFD2 in immersion fixed frozen sections of embryonic mouse brain (E10, neural tube). Samples were incubated in MCFD2 polyclonal antibody (Product # PA5-48016) using a dilution of 10 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to secretion.
产品信息
PA5-48016
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse SDNSF/MCFD2 His27-Gln145
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2606748
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause of factor V and factor VIII combined deficiency (F5F8D). F5F8D is an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Multiple coagulation factor deficiency protein 2 homolog; neural stem cell derived neuronal survival protein; Neural stem cell-derived neuronal survival protein
基因别名: 1810021C21Rik; F5f8d; Lman1ip; Mcfd2; Sdnsf
UniProt ID: (Mouse) Q8K5B2
Entrez Gene ID: (Mouse) 193813
